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@ -63,7 +63,7 @@ If you are doing gamete storage, you may be able to get some limited feminizing
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In terms of safety, the general wisdom is that: pharmaceutical grade > reputable home-brewer > personally home-brewing.
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However, if you have no other option, brewing at home from raws is possible.
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However, if you have no other option, brewing at home from raws is possible.
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A good page for learning about this is this [Homebrewing Wiki Page](https://hrtcafe.net/Homebrew/){.source-link}.
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@ -108,12 +108,15 @@ Here are some guides:
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- [Comparison of sources of GLP Drugs](https://www.finnrick.com/)
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- [Long post discussing GLP Drugs](https://www.cremieux.xyz/p/how-to-get-cheap-ozempic){.source-link}
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- [Sleep, Diet, Exercise and GLP-1 Drugs](https://thezvi.substack.com/p/sleep-diet-exercise-and-glp-1-drugs){.source-link}
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- [The bio-pirate's guide to GLP-1 agonists](https://www.lesswrong.com/posts/coLiSHpP338Xwibbp/the-bio-pirate-s-guide-to-glp-1-agonists#fnref-LYLQjJzcJtaBLesWp-6){.source-link}
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For some discussion on people's experiences, you can read online. Read for example:
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- [30 days on retatrutide](https://www.lesswrong.com/posts/mLvek6a9G86EnhJqH/30-days-of-retatrutide){.source-link}
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- [a 9-week trip on retatrutide](https://www.lesswrong.com/posts/J8nvbu5AFqR5ysSDR/a-9-week-trip-on-retatrutide){.source-link}
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If you decided to order, probably look on finnrick, and chose the more reputable chinese sellers with good lab results but sketchy websites where you order via whatsapp, as it is like 10x cheaper than non-china based resellers (typically costing like 10 vials for the same as 1 on other sites), though shipping will cost slightly more and take longer.
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#### Corset diet.
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Wearing a corset can also reduce appetite. You can do this in addition to [Waist Training](#waist-training) to also further reduce waist-to-hip ratio in the mean time. See section that for more info.
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@ -776,7 +779,7 @@ Link to article about it:
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### Avoiding scarring
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If cut, there is potential research on avoiding scar tissue from forming.
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If cut, there is potential research on avoiding scar tissue from forming.
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#### Verteporfin
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@ -0,0 +1,189 @@
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<meta charset='utf-8'>
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<base target='_blank'>
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<style>
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body{font-family:system-ui,sans-serif;max-width:50rem;margin:2rem auto;line-height:1.6;padding:1rem}
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img,iframe{max-width:100%}
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.archive-header{background:#f0f8ff;border:1px solid #e0e0e0;border-radius:5px;padding:0.75rem;margin-bottom:1rem;font-size:0.9rem}
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.archive-header{background:#1a1a2e;border-color:#333;color:#e0e0e0}
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.archive-header a{color:#66b3ff}
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}
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</style>
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<div class="archive-header">
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<div class="archive-info">
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<strong>📄 Archived:</strong> 2026-01-05 00:14:03 UTC
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</div>
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<div class="archive-source">
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<strong>🔗 Source:</strong> <a href="https://deschamps-braly.com/jaw-contouring-ffs-and-wisdom-teeth/">https://deschamps-braly.com/jaw-contouring-ffs-and-wisdom-teeth/</a>
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</div>
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</div>
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<script>
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// Archive metadata for cache management
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window.archiveData = {
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url: 'https://deschamps-braly.com/jaw-contouring-ffs-and-wisdom-teeth/',
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archivedAt: "2026-01-05T00:14:03.121788+00:00Z",
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timestamp: 1767572043121
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};
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</script>
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<hr>
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<h1>Jaw Contouring for FFS and Wisdom Teeth</h1>
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<main>
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<section class="pay-it-forward-banner short-banner position-relative common-background-style d-flex align-items-end" style="background-image: url(https://deschamps-braly.com/wp-content/uploads/2025/10/FFS_jaw-contouring.jpg);">
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<div class="container">
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<div class="pay-it-forward-banner-wrapper">
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<h1>
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<span>Jaw Surgery</span>
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Jaw Contouring for FFS and Wisdom Teeth </h1>
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</div>
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</div>
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</section>
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<section class="blog-post-area">
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<div class="container">
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<div class="blog-post-wrapper">
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<div class="row">
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<div class="col-lg-3">
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<div class="sidebar-area">
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<div class="slidbar-head">
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<h4>Page Summary</h4>
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</div>
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<div class="sidebar" id="sidebar-quicklinks"></div>
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</div>
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</div>
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<div class="col-lg-9">
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<div class="row">
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<div class="col-lg-9">
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<div class="contents">
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<!-- ================ Page Content =================== -->
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<p><img alt="" class="alignnone size-full wp-image-4033" decoding="async" fetchpriority="high" height="577" src="https://deschamps-braly.com/wp-content/uploads/2025/10/FFS_jaw-contouring.jpg" width="865"/></p>
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<h2>JAW CONTOURING FOR FACIAL FEMINIZATION SURGERY AND EXTRACTION OF WISDOM TEETH</h2>
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<p>If you are considering <a href="https://deschamps-braly.com/facial-feminization-surgery/" rel="noopener noreferrer" target="_blank">facial feminization surgery (FFS)</a> and you haven’t had your wisdom teeth removed, we recommend an analysis of the state of your teeth and an integrated approach to any surgeries required.</p>
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<p>Removing your wisdom teeth – or any other <a href="https://deschamps-braly.com/jaw-surgery-and-FFS" rel="noopener noreferrer" target="_blank">corrective surgery to your jaw</a> – can impact the overall aesthetics of your face and is best considered in the context of any future FFS.</p>
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<p>Consulting with plastic surgeons trained in multiple surgical specialties and with proven expertise in the artistry of facial feminization, such as Dr. Deschamps-Braly, has the advantage of facilitating an integrated approach and optimal timing for any surgeries needed for your oral health and aesthetic surgery and is more likely to give you the best possible result.</p>
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<h2>THE CASE FOR REMOVING WISDOM TEETH BEFORE FFS</h2>
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<p>Most people have 32 permanent adult teeth, with four wisdom teeth emerging between 17 years of age and the early 20s. Typically, one wisdom tooth is located at the very back of each row of teeth on each side of the upper and lower jaw.</p>
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<p>In many people, the wisdom teeth become <strong>impacted</strong> – meaning they will emerge and collide with the other molars. There are different degrees of impaction, but in general it can create problems including:</p>
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<ul>
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<li>Difficulty in cleaning</li>
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<li>Infection & cysts</li>
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<li>Crowding of the teeth that force the positioning of other teeth to become irregular, especially at the front</li>
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<li>Damage and pressure on neighboring teeth</li>
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<li>Wisdom teeth that cannot emerge and remain embedded in the jaw bone</li>
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</ul>
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<p>Some people don’t have their wisdom teeth removed as young adults because the teeth wouldn’t cause problems. But as you age, the roots of wisdom teeth become longer and the jaw bone becomes denser which means problems become more likely.</p>
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<p>Problems with wisdom teeth can occur at any time but are more likely to occur in your 30s. In addition, the removal of wisdom teeth is more likely to cause complications when you are older, as the roots have grown further into the bone.</p>
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<p>For all these reasons, if you are considering FFS, we recommend thinking about removing your wisdom teeth before undergoing a jaw reduction surgery. If problems with the teeth emerge after FFS, extracting the wisdom teeth may affect any previous <a href="https://deschamps-braly.com/surgical/facial-feminization/jaw-contouring/">jaw surgery</a> and affect the overall aesthetics of the feminine face you worked so hard to achieve.</p>
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<h2>ADVANTAGES OF HAVING FFS AFTER EXTRACTION OF WISDOM TEETH</h2>
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<p>In terms of the aesthetics of the face, some people find removing their wisdom teeth makes their jaw appear narrower and their facial features have a more feminine appearance. While some might consider this a benefit, especially in their youth, others have reported their face appeared gaunt and looked older.</p>
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<p>Your <a href="https://deschamps-braly.com/facial-feminization-surgery/facial-feminization-surgery/" rel="noopener noreferrer" target="_blank">FFS surgery</a> is best designed to correct and perfect your look after you have had any other structural surgeries to your jaw such as extraction of wisdom teeth or corrective jaw surgery (<a href="https://deschamps-braly.com/jaw-surgery-and-FFS" rel="noopener noreferrer" target="_blank">orthognathic surgery</a>).</p>
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<h2>EXTRACTION OF WISDOM TEETH BEFORE FFS CAN HAVE THE FOLLOWING BENEFITS:</h2>
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<ul>
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<li>If you are unhappy with the way your face looks once wisdom teeth have been removed (gaunt cheeks, aging, etc.), you can discuss the potential for improving the aesthetics of your face during FFS.</li>
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<li>Without wisdom teeth, the surgeon can more easily design any jaw bone cuts required to give you the best result with FFS – the presence of wisdom teeth can affect Dr. Deschamps-Braly ability to cut your jaw bone.</li>
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<li>Any previous <a href="https://deschamps-braly.com/facial-feminization-surgery/jaw-shaping/">jaw contouring</a> for FFS might affect the outcomes of wisdom tooth extraction, especially if you are older than your early 20s and the roots of your wisdom teeth have grown further into your bone.</li>
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<li>If you have more serious complications after tooth extraction, you might need further surgeries that might affect the aesthetics of your face.</li>
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<li>Any asymmetries in your jawline after wisdom teeth have been removed can potentially be corrected by FFS.</li>
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</ul>
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<h2>DISADVANTAGES OF REMOVING WISDOM TEETH AFTER FFS</h2>
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<p>Like any medical procedure, removing wisdom teeth can have complications, especially if you have a severe impaction requiring a more complex surgical procedure.</p>
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<p>Depending on the position of your wisdom teeth and your age, extraction can affect your jawbones and cheeks, especially if you are older than your early 20s. Anything that affects your upper jaw, lower jaw or cheeks could impact the aesthetics of the look you have achieved with previous facial reconstructive surgery.</p>
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<p>Even if there are no complications, some people just don’t like the way their face looks after their wisdom teeth have been removed. Correcting this might require more surgical procedures.</p>
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<h3>POTENTIAL CONSEQUENCES OF WISDOM TOOTH REMOVAL ON FFS SURGERY</h3>
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<p>Extraction of wisdom teeth can cause short-term complications that are less likely to affect previous FFS, including:</p>
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<ul>
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<li>Temporary swelling of the cheeks and jaw in the days after the procedure</li>
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<li>Infection – can be treated with medication or draining and cleaning of the area</li>
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<li>Dry sockets – caused by the loss of the blood clot in the empty tooth socket</li>
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</ul>
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<p>Other complications that could impact the aesthetics achieved with previous FFS surgery include:</p>
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<ul>
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<li>Damage to nearby teeth</li>
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<li>Damage to the sensory nerve in the lower jaw – usually temporary tingling or numbness in the lower lip, chin, or tongue</li>
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<li>Lower jaw bone breaks</li>
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<li>Sinus communication – removal of upper teeth can create an opening between your mouth and sinuses</li>
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</ul>
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<h2>Want to know more?</h2>
|
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<ul>
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<li><a href="https://deschamps-braly.com/jaw-surgery/">Orthognathic (Jaw) Surgery</a></li>
|
||||
<li><a href="https://deschamps-braly.com/facial-feminization-surgery/jaw-shaping/">Jaw Contouring (Reshaping/Tapering)</a></li>
|
||||
<li><a href="https://deschamps-braly.com/facial-feminization-surgery/">Facial Feminization Surgery – Overview</a></li>
|
||||
<li><a href="https://deschamps-braly.com/key-elements-ffs-for-women-masculine-faces/">Key Elements of Facial Feminization for Women with Masculine-Looking Faces</a></li>
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<li><a href="https://deschamps-braly.com/ffs-v-line-vs-jaw-surgery/">Considering Facial Feminization? Unsure About V-Line Surgery vs Feminizing Jaw Surgery?</a></li>
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||||
</ul>
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||||
<h2>References – for those who like to dig deeper</h2>
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<ul>
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<li><a href="https://www.google.com/url?q=https://doi.org/10.1097/SCS.0000000000005391&sa=D&ust=1563237185777000&usg=AFQjCNGAAYKdBwG0Qo6uGumOYZmrW1RFFA" rel="noopener noreferrer" target="_blank">Approach to Feminization Surgery and Facial Masculinization Surgery</a>: Aesthetic Goals and<br/>
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Principles of Management.</li>
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<li>Deschamps-Braly JC. Journal of Craniofacial Surgery, 2019; Apr 2 [Epub ahead of print].</li>
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<li><a href="https://doi.org/10.1016/j.fsc.2019.01.002" rel="noopener noreferrer" target="_blank">Feminization of the Chin: Genioplasty Using Osteotomies</a>.</li>
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<li>Deschamps-Braly J. Facial Plastic Surgery Clinics of North America, 2019;27(2):243–250.</li>
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</ul>
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<!-- ================ End :: Page Content ============ -->
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</div>
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</div>
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<div class="col-lg-3">
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<div class="blog-category-right">
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<h4>Categories:</h4>
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<ul>
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<li><a href="https://deschamps-braly.com/category/craniofacial/">Craniofacial</a></li>
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||||
<li><a href="https://deschamps-braly.com/category/dlm-faq/">DLM FAQ</a></li>
|
||||
<li><a href="https://deschamps-braly.com/category/facial-feminization-surgery/">Facial Feminization Surgery</a></li>
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||||
<li><a href="https://deschamps-braly.com/category/facial-implants/">Facial Implants</a></li>
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<li><a href="https://deschamps-braly.com/category/facial-masculinization-surgery/">Facial Masculinization Surgery</a></li>
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<li><a href="https://deschamps-braly.com/category/injectables/">Injectables</a></li>
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<li><a href="https://deschamps-braly.com/category/jaw-surgery/">Jaw Surgery</a></li>
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<li><a href="https://deschamps-braly.com/category/non-surgical/">Non-Surgical</a></li>
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||||
<li><a href="https://deschamps-braly.com/category/nose/">Nose</a></li>
|
||||
<li><a href="https://deschamps-braly.com/category/office-news/">Office News</a></li>
|
||||
<li><a href="https://deschamps-braly.com/category/plastic-surgery/">Plastic Surgery</a></li>
|
||||
</ul>
|
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<h4>About Deschamp- Braly Clinic:</h4>
|
||||
<p>We are privileged to be a part of a journey where the destination is a place that brings you a renewed sense of happiness. We are here to give you our very best. Most importantly, we are here to share in your sense of relief and joy as the dressings are removed.</p>
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<h4>Share Post:</h4>
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|
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<section class="discover-more-sec full-width">
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|
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<h2 id="discover-more-18">Discover More</h2>
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<img alt="Educational Videos Image" class="w-100" src="https://deschamps-braly.com/wp-content/uploads/2025/09/discover-more1.png"/>
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<h3><a href="https://deschamps-braly.com/resources/educational-videos/">Educational Videos</a></h3>
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<h3><a href="https://deschamps-braly.com/resources/patient-reviews/">Patient Reviews</a></h3>
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<img alt="Meet The Team Image" class="w-100" src="https://deschamps-braly.com/wp-content/uploads/2025/11/Meet-The-Team-Featured.jpg"/>
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<h3><a href="https://deschamps-braly.com/about-us/meet-the-team/">Meet The Team</a></h3>
|
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|
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<img alt="Fly In For Surgery Image" class="w-100" src="https://deschamps-braly.com/wp-content/uploads/2025/09/discover-more4.png"/>
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<h3><a href="https://deschamps-braly.com/fly-in-for-surgery/">Fly In For Surgery</a></h3>
|
||||
</div>
|
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</div>
|
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|
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</div>
|
||||
</section>
|
||||
</main>
|
||||
@ -0,0 +1,109 @@
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<meta charset='utf-8'>
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<base target='_blank'>
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<style>
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body{font-family:system-ui,sans-serif;max-width:50rem;margin:2rem auto;line-height:1.6;padding:1rem}
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img,iframe{max-width:100%}
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.post-content{background:#f9f9f9;padding:1rem;border-radius:5px;margin:1rem 0}
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.archive-header{background:#f0f8ff;border:1px solid #e0e0e0;border-radius:5px;padding:0.75rem;margin-bottom:1rem;font-size:0.9rem}
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.archive-info{margin-bottom:0.5rem;color:#666}
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@media (prefers-color-scheme: dark) {
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.archive-header{background:#1a1a2e;border-color:#333;color:#e0e0e0}
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</style>
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<div class="archive-header">
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<div class="archive-info">
|
||||
<strong>📄 Archived:</strong> 2026-01-05 00:14:04 UTC
|
||||
</div>
|
||||
<div class="archive-source">
|
||||
<strong>🔗 Source:</strong> <a href="https://www.lesswrong.com/posts/coLiSHpP338Xwibbp/the-bio-pirate-s-guide-to-glp-1-agonists#fnref-LYLQjJzcJtaBLesWp-6">https://www.lesswrong.com/posts/coLiSHpP338Xwibbp/the-bio-pirate-s-guide-to-glp-1-agonists#fnref-LYLQjJzcJtaBLesWp-6</a>
|
||||
</div>
|
||||
</div>
|
||||
<script>
|
||||
// Archive metadata for cache management
|
||||
window.archiveData = {
|
||||
url: 'https://www.lesswrong.com/posts/coLiSHpP338Xwibbp/the-bio-pirate-s-guide-to-glp-1-agonists#fnref-LYLQjJzcJtaBLesWp-6',
|
||||
archivedAt: "2026-01-05T00:14:04.504712+00:00Z",
|
||||
timestamp: 1767572044504
|
||||
};
|
||||
</script>
|
||||
<hr>
|
||||
<h1>The bio-pirate's guide to GLP-1 agonists</h1>
|
||||
<html><body><div><div><p id="block0">How to lose weight, infringe patents, <s>and possibly poison yourself</s> for 22 Euros a month.</p>
|
||||
<h2 id="Introduction">Introduction</h2>
|
||||
<p id="block1">In March 2025, Scott Alexander <span><span><a href="https://www.astralcodexten.com/p/the-ozempocalypse-is-nigh">wrote</a></span></span>:</p>
|
||||
<blockquote id="block2">
|
||||
<p id="block3">Others are turning amateur chemist. You can order GLP-1 peptides from China for cheap. Once you have the peptide, all you have to do is put it in the right amount of bacteriostatic water. In theory this is no harder than any other mix-powder-with-water task. But this time if you do anything wrong, or are insufficiently clean, you can give yourself a horrible infection, or inactivate the drug, or accidentally take 100x too much of the drug and end up with negative weight and float up into the sky and be lost forever. ACX cannot in good conscience recommend this cheap, common, and awesome solution.</p>
|
||||
</blockquote>
|
||||
<p id="block4">With a BMI of about 28, low executive function, a bit of sleep apnea and no willpower to spend on either dieting or dealing with the medical priesthood, I thought I would give it a try. This is a summary of my journey.</p>
|
||||
<p id="block5">Please do not expect any great revelations here beyond "you can buy semaglutide from China, duh". All of the details here can also be found elsewhere, still I thought it might be helpful to write them down.</p>
|
||||
<p id="block6">Also be careful when following medical advise from random people from the internet. <span class="blockquote_JoQjsHjtbwQuyGaWa_1"><span class=""><span></span>The medical system is full of safeguards to make very sure that no procedure it does will ever hurt you.</span></span> Here you are on your own. I am not a physician, just an interested amateur with a STEM background. If you do not know if it is ok to reuse syringes or inject air, or do not trust yourself to calculate your dose, I would recommend refraining from DIY medicine.</p>
|
||||
<h2 id="Picking_a_substance_and_route_of_administration">Picking a substance and route of administration</h2>
|
||||
<p id="block7">The two main approved GLP-1 agonists are <span><span><a href="https://en.wikipedia.org/wiki/Tirzepatide">tirzepatide</a></span></span> and <span><span><a href="https://en.wikipedia.org/wiki/Semaglutide">semaglutide</a></span></span>. Both are peptides (mini-proteins) with a mass of about 4-5kDa which cost approximately the same to produce. A typical long term dose of tirzepatide is 15mg/week, while semaglutide is 2.4mg/week, so I focused on sema because it looked like the cheaper option.<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-1" data-footnote-index="1" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-1" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-1">[1]</a></span></sup>
|
||||
</span></p>
|
||||
<p id="block8">While I would have preferred oral to subcutaneous injection, the bioavailability of oral semaglutide is kinda terrible, with typical long term doses around 14mg/day -- forty times the amount of subcutaneous injection. So I resolved to deal with the hassle of poking myself with needles and possibly giving myself 'horrible infections'.</p>
|
||||
<p id="block9">Given that the long term dosage is 2.4mg/week, and that sources generally state that once opened, vials should be used within four (or <span><span><a href="https://www.thepeptidereport.com/mixing-semaglutide-with-bacteriostatic-water-a-how-to-guide/#Storage_and_Handling_of_the_Mixed_Solution">eight</a></span></span>) weeks, I decided that the optimal vial size would be 10mg -- enough for four weeks. <span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-2" data-footnote-index="2" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-2" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-2">[2]</a></span></sup>
|
||||
</span></p>
|
||||
<h2 id="Finding_a_vendor">Finding a vendor</h2>
|
||||
<p id="block10">So I started searching the web for possible vendors of lyophilized semaglutide. I found a wide range of prices from 250$ for a 10mg vial (which would last four weeks at maximum dosage) down to about 50$. And a single website which offered ten vials of 5mg each for 130$.</p>
|
||||
<p id="block11">That one seemed to be a Chinese manufacturer of organic compounds<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-3" data-footnote-index="3" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-3" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-3">[3]</a></span></sup>
|
||||
</span>. Slightly broken English, endless lists of chemicals by CAS number, no working search function on the website, outdated and incomplete price info provided as a jpeg on the site. I figured that if it was a scam site, it was matching very well to my preconception of how a site of a company more enthusiastic about synthesis than selling to consumers would look like, and contacted them. After I was provided with current pricing (also as a series of jpegs), I sent them about 200 Euros worth of BTC<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-4" data-footnote-index="4" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-4" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-4">[4]</a></span></sup>
|
||||
</span> for ten 10mg vials plus shipping. (Shipping was 70$, probably indicative of a preference to sell in larger quantities.)</p>
|
||||
<p id="block12">A week or so later, I got my delivery. Ten unmarked vials, of a volume of about 3ml each, filled to perhaps a third with a block of white stuff.<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-5" data-footnote-index="5" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-5" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-5">[5]</a></span></sup>
|
||||
</span></p>
|
||||
<p id="block13">I would have preferred to have a quantitative analysis of the contents, but all the companies in Germany I contacted were either unwilling to deal with consumers or unable to perform HPLC-MS, so I reasoned that the vendor would be unlikely to sell me vials filled with botulinum toxin instead <span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-6" data-footnote-index="6" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-6" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-6">[6]</a></span></sup>
|
||||
</span>, and just started with injecting myself with 1/40th of a vial per week, which would amount to 0.25mg if the content was as advertised.</p>
|
||||
<p id="block14">(<span class="blockquote_2Dv9uq8dtxxqkgZrZ_1">If anyone has a great, affordable way for peptide analysis, please let me know in the comments!)</span></p>
|
||||
<h2 id="Sourcing_bacteriostatic_water">Sourcing bacteriostatic water</h2>
|
||||
<p id="block15">Unlike random pharmaceuticals, bacteriostatic water can be legally sold in Germany. Sadly, it would have cost me almost as much as the active ingredient, about 15 Euro per vial. So instead, I decided to craft my own bacteriostatic water. I sourced a lifetime supply of benzyl alcohol for a couple of Euros. Instead of dealing with distilled water, I bought sealed medical grade plastic vials of 0.9% NaCl solution "for inhalation", roughly 0.5 Euro a piece. Once a month, I add 0.1ml benzyl alcohol (naturally sterile) to one 5ml plastic vial, which gives me about 2% benzyl alcohol, which is twice of what is specified as BAC, erring on the side of caution (and tissue damage from alcohol, I guess).</p>
|
||||
<h2 id="Other_equipment">Other equipment</h2>
|
||||
<p id="block16">I already had a bunch of sterile 20G hypodermic needles and 3ml syringes from another project. For injection of minute quantities of liquids into my body, I bought sterile 1ml insulin syringes with 6mm, 31G needles (@0.3 Euro).<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-7" data-footnote-index="7" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-7" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-7">[7]</a></span></sup>
|
||||
</span></p>
|
||||
<p id="block17">Happily, I owned a fridge and a disinfectant spray, completing my toolset.</p>
|
||||
<h2 id="My_current_procedure">My current procedure</h2>
|
||||
<p id="block18">Every four weeks, I will prepare a new vial. I prefer to fill the vials with 3ml of my BAC+, which should give 3.3mg/ml of sema.</p>
|
||||
<p id="block19">Apply disinfectant to hands and workspace to taste. Then, start with opening a new plastic vial of NaCl. Using an insulin syringe, add 0.1ml benzyl alcohol to it. Unseal a 3ml syringe and needle and draw and release your BAC+ from the plastic vial a few times to mix it. Now draw 3ml of that, tear off the plastic cap<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-8" data-footnote-index="8" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-8" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-8">[8]</a></span></sup>
|
||||
</span> of your new glass vial, stick the needle through the rubber seal and slowly inject your BAC into the vial. The vial will be low-pressure, so getting liquid into it is really easy. Shake a bit and wait for the lyophilized peptide to dissolve. Store it in a fridge (preferably in the plastic box with the other vials), and liberally apply disinfectant to the rubber seal before and after each use.</p>
|
||||
<p id="block20">To draw a dose, first figure out the volume you need. Disinfect, unseal your 1ml syringe, first inject an equal amount of air into the vial, then turn the vial rubber side down and draw the liquid. To start with, I would recommend drawing 0.1ml more than you need, because you will likely have some air bubbles in. Remove the needle, get rid of the excess air (and excess liquid). Check that you are in a private place, expose your tights, apply disinfectant, pinch the skin of your tight with two fingers, stick in the needle with the other hand, push down the plunger. Cover up your tights, put your vial back into the fridge, safely dispose of your needle.<span class="footnote-reference" data-footnote-id="-LYLQjJzcJtaBLesWp-9" data-footnote-index="9" data-footnote-reference="" id="fnref-LYLQjJzcJtaBLesWp-9" role="doc-noteref">
|
||||
<sup><span><a class="" href="#fn-LYLQjJzcJtaBLesWp-9">[9]</a></span></sup>
|
||||
</span></p>
|
||||
<h2 id="Outcome___N_1_">Outcome (<span class="mjpage"><span class="mjx-chtml"><span aria-label="N=1" class="mjx-math"><span aria-hidden="true" class="mjx-mrow"><span class="mjx-mi"><span class="mjx-char MJXc-TeX-math-I">N</span></span><span class="mjx-mo MJXc-space3"><span class="mjx-char MJXc-TeX-main-R">=</span></span><span class="mjx-mn MJXc-space3"><span class="mjx-char MJXc-TeX-main-R">1</span></span></span></span></span></span>)</h2>
|
||||
<p id="block21">Having taken semaglutide as scheduled for some 22 weeks, I have recently cut my dosage in half because I have reached a BMI of 22.</p>
|
||||
<p id="block22">Traditionally, weight loss was seen as a moral battle: eat less than you want to eat, eat different things than you want to eat, do more sports than you want to do. Basically, spend willpower points to lose weight.</p>
|
||||
<p id="block23">GLP-1 agonists are a cheat code, like reaching enlightenment through psychedelics instead of years of meditation, or bringing a gun to a sword fight. I literally spend zero willpower points in this endeavor. I continue to eat what I want and how much I want, it just so happens I want less food. I am under no illusion that this cheat will give me the full benefits of exercise and proper diet. But realistically, these were never an option for me (until someone discovers an infinite willpower cheat).</p>
|
||||
<p id="block24">Will I rebounce once I quit sema? Not a problem, at 20 Euros a month, the drug pays itself in money not spend on chocolate, and it is less of a hassle than taking my other pills once a day, so I am willing to continue to take it for the rest of my life.</p>
|
||||
<p id="block25">Thanks to Scott Alexander for pointing out this option and to my Chinese vendor for providing Westerners like myself with cheap bodily autonomy.</p>
|
||||
<p id="block26">Up next: <em>The bio-pirate's guide to DIY MAID</em> (due in a few decades, <span><span><a href="https://thingofthings.substack.com/p/on-present-rate-no-singularity">PRNS</a></span></span>).</p>
|
||||
<ol class="footnote-section footnotes" data-footnote-section="" role="doc-endnotes"><li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-1" data-footnote-index="1" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-1" role="doc-endnote"><p id="block28">I should probably add that the price difference is not all that large. 60mg tirzepatide vials cost perhaps twice as much as 10mg sema vials, because a lot of it is dose-independent overhead. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-1">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-2" data-footnote-index="2" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-2" role="doc-endnote"><p id="block30">Also note that the standard recommended dose schedule calls for minimal doses at the start, which will come down to 75uL. This would be even less convenient using 20mg/vial. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-2">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-3" data-footnote-index="3" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-3" role="doc-endnote"><p id="block32">The sha1-sum of their 14-character domain name is <code>6682ca2d70b203e0487c49d868ea20401b5ede1c</code>. Note that I can not vouch for their production chain (obviously), but am personally very happy with my dealings with them and plan to buy my next pack of vials from them as well. I do not want to link them to avoid this looking like a sketchy drug advertisement. DM me if you can't find them. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-3">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-4" data-footnote-index="4" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-4" role="doc-endnote"><p id="block34">Their slightly unfavorable exchange rate for bitcoin happily negated the exchange rate between US$ and Euro, simplifying my calculations here. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-4">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-5" data-footnote-index="5" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-5" role="doc-endnote"><p id="block36">I was suspicious about that amount, as I would have imagined that 10mg would be a lot less. While I do not have a scale on that level of precision, I confirmed that the residue of a dried droplet was much less indeed. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-5">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-6" data-footnote-index="6" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-6" role="doc-endnote"><p id="block38">If I had been wrong about that, I would at least have contributed to raising the sanity waterline. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-6">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-7" data-footnote-index="7" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-7" role="doc-endnote"><p id="block40">Obligatory whining about excessive paternalism: A few years ago, I could buy medical grade syringes and needles (Braun) from Amazon Germany. These days, all the offers say "for research purposes only". When did society decide that people having access to medical grade equipment for any purpose was a bad thing? Is anyone under the impression that not providing heroin addicts, needleplay enthusiasts, or peptide enjoyers will result in them abstaining from risky behavior? <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-7">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-8" data-footnote-index="8" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-8" role="doc-endnote"><p id="block42">When I was taking ketamine for depression (filling injection vials into a nasal spray), I did not know about the plastic caps. Turns out it is really hard to pierce them with a hypodermic needle. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-8">↩︎</a></p>
|
||||
</li>
|
||||
<li class="footnote-item" data-footnote-id="-LYLQjJzcJtaBLesWp-9" data-footnote-index="9" data-footnote-item="" id="fn-LYLQjJzcJtaBLesWp-9" role="doc-endnote"><p id="block44">I recap, which is fine here because I already have all the pathogens in my blood which might be on the needle, and then collect the needles in an empty bottle for disposal. <a class="footnote-backref" href="#fnref-LYLQjJzcJtaBLesWp-9">↩︎</a></p>
|
||||
</li>
|
||||
</ol></div></div></body></html>
|
||||
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Reference in New Issue
Block a user