📄 Archived: 2025-08-06 17:06:00 UTC
🔗 Source: https://old.reddit.com/r/DIYCosmeticProcedures/comments/18onbl8/adifyline_update_explanation/

# Adifyline update: explanation

r/DIYCosmeticProcedures • by u/anniesiaccc • 48 points

Hey guys I originally posted back in October about ordering adifyline (hexapeptide) for 13$ online and started my daily protocol of topically applying basic lotion that i put the peptide in. For anyone who doesn’t know- adifyline, when applied topically to areas that maintain adipose-cutaneous fatty tissue- it will generate more fat to that area, so it can be used for breast cup growth, cheek volume, etc Well, I didn’t post my update because I made the choice of doing a diy CaHa (hyperdilluted) on my face, and the photos would reflect that as opposed to yielding true results. I do want to say, that using it on the breasts has made my boobs massive (I am 30 but have sported A cups/ small B’s my whole life until they drastically got bigger and fuller after about one month in using ritualistically, so last month in November they became and still are a heavy C.) I will also say, if you use this be cautious of where you apply if it’s on your body because you will get bigger. If you want bigger hips this is your go to. I made the mistake of putting it on my butt and I feel like an hourglass and I don’t like it perhaps because I wasn’t ready for such a transition but I will literally be using lemon bottle or something (please shoot me recommendations) to reverse what I thought I wanted on certain areas 🥴🫠 To anyone who has used, would love to hear if you experienced similar And to anyone curious feel free to ask questions Happy holidays, peace love and D-I- fucking -Y

## Comments

u/Downtown-Trip3501 • 17 points

May I please see before and afters? So interested!

u/sakurababydoll • 12 points

why get a bbl when you can use adifyline 🤣

u/TheKnown_Unknown • 1 points

this made me laugh lool, did you try it?

u/KiwiAvocados • 13 points

Can you share your mixing ratio please?

u/ohuwish • 10 points

How did you find out about this? I’ve never heard of it

u/anniesiaccc • 18 points

I was big into researching peptides for anti aging and trying to find something for skin plumping for the last year and a half and finally came across a research study about Adifyline (Ill follow up with some links later but may need y’all to remind me!) however this wasn’t yet able to be purchased anywhere so I let I go. Then this October I kind of went down a similar rabbit hole after someone on this forum asked about it and a few users provided some links, in which one I clicked and purchased for 13 bucks :) For the sources I’d go to the search bar and type “adefyline” in this subreddit and you’ll find it I believe the title was about sunken cheeks lol

u/badkittenatl • 7 points

Can you post those? And some before and afters?

u/TheKnown_Unknown • 1 points

oh this is so cool, would love to hear more about how adifyline has been since, and what actually seemed most promising for anti aging/skin plumping in the end from what you saw/read?

u/CompetitiveBass3644 • 21 points

I need more info. My ozempic butt is bad

u/RedditKon • 7 points

Same lol. Mounjaro Butt

u/lunago92 • 6 points

I got the mounjaro butt too 😩 looks like I’m wearing a saggy skin diaper

u/[deleted] • 1 points

Have you figured out what to do about it?

u/cybilinside • 3 points

Work out. I mean you can grow more fat on your butt, yeah, but if you want it to stop sagging you're going to have to build that muscle. I've been doing it for 3 mo this months now 5 days a week and I'm just now starting to see more actual roundness to my butt again. Wish I could say the same about my boobs..... They're just pitiful.

u/fatal-prophecy • 17 points

WOW! That's unbelievable you were able to achieve such massive results non-surgically, let alone topically! I'm not accusing you of lying (what would be the point anyway) as this is the first time I've even heard of peptides being used for this purpose and being so effective. But holy shit it sounds like a miracle. I'm about to embark on this quest myself I mean there's nothing to lose at that kind of price. Did you buy it here @ lotioncrafter - the 8gs for $14?? And you just mixed it in with a lotion? That's crazy you could go from an A to a C cup with something so minimal like that. But I definitely want to try it now myself.

u/anniesiaccc • 12 points

Yes lotion crafter!!!! That’s the stuff! I wasn’t able to see with clarity how it altered my face granted my fillers I did but, yeah, it made my body grow in 2 months MASSIVE. All I did was rub the lotion I put maybe 1/4th of the vial (it comes with. Dropper attachment for easy mixing) into a huge bottle of dove lotion and rub it on every day and sometimes before bed. I’m still adjusting to how I look but it’s what I asked for so I can say it delivered. If you get it please let me know your journey & i wish you the best of beauty!! 💛💛

u/fatal-prophecy • 9 points

That's sooo crazy you had such insane results. I'm happy for you but holy shit it seems like a genuine miracle, not just that it's topical but also in such a highly diluted form. Even lotioncrafter (and other sites) recommend a usage rate of 2% but it says their product is 0.05? I'm just so confused lol. But am gonna test it out anyway, it's not like there's much to lose...Hell I'd be overjoyed just to get a 1/2 cup size improvement. Tbh I was strongly considering buying the estrogen that transwomen use but supposedly there's serious risks with that soo yeah this would be way better lol.

u/theejswann • 3 points

What have been your results?

u/cybilinside • 2 points

Have you had any results?

u/FishMcBobson • 2 points

How much did you add to how much lotion please? I’d love similar results

u/TheKnown_Unknown • 1 points

how did this quest go? starting myself atm

u/Sarahlb76 • 8 points

Ok but if it increases fat, does it increase cellulite? I’m skinny fat. Like I’m super thin with cellulite. I’d love an actual butt but don’t want more cellulite!

u/anniesiaccc • 8 points

I don’t think it plays a role in cellulite any more than fat does as from what I understand cellulite is more so a result of fat dispersal and this peptide generates adipose tissue (cutaneous fat)

u/Status_Ad_4230 • 1 points

Lift weights. Dance. Getvthat booty

u/InvestigatorHot8127 • 7 points

I want to add to my butt. Do you just rub it on? Does it ever get uneven?

u/theejswann • 1 points

😂😂🤣

u/InvestigatorHot8127 • 2 points

I still want to rub it on my butt. My butt could use a little more fat. 😂🍑

u/Curious-Cappuccino • 4 points

Wow! Do you know what happens if you stop using it? Will the effects diminish and go back to normal?

u/anniesiaccc • 7 points

I don’t know what happens after discontinuing except for my experience which was that it stayed and won’t go away.. hah

u/theejswann • 3 points

How about now? Any change in the results? lol

u/Melodic-Psychology62 • 4 points

What a goddess send! I have used diy skin cream for years as it’s so very easy and less expensive than store bought. Never found this company!

u/kvltWitch • 3 points

Wow so I was looking into adipeau cream but the reviews of the company being scammy scared me away. I think I’d like to try this! I read it only works where there are hair follicles, though.

I’m wondering if I microneedle first on places with few hair follicles if I’d get decent results. I’m looking specifically for my temples. Filler there hurts so badly 😭😭

u/anniesiaccc • 3 points

I did on my face and noticed an instant effect. I can’t speak for the long term because I compromised my self experimentation on my face by being impatient and using ca-ha fillers, but I did the boobs routinely at least 6 weeks & butt like 3 times and I have always been thinner and now I am stuck with a curved bod

u/kvltWitch • 5 points

Wow!! It’s absolutely crazy that a topical can do that. I went to lotion crafters and I saw a bunch of additives that supposedly MELT fat too! Wild, I’m totally experimenting with both lol Thank you!!

u/anniesiaccc • 6 points

Melt?!? I need to know about this if it works! I’m a strong believer in “if it seems too good to be true, it likely is-“ Hence why I stand corrected with this I haven’t heard of fat melting topicals and am kinda skeptical but please dooo keep me updated on your journey if it works! Much love

u/kvltWitch • 3 points

https://lotioncrafter.com/products/actigym?variant=13079564976217

Does seem too good to be true but I love being a guinea pig! I

u/Background-Limit-358 • 2 points

id love to be a guinea pig with you!! did you purchase?

u/Background-Limit-358 • 3 points

adipeau is by no means a scam. the founder is incredibly smart. i’ve been using for 6 weeks and major changes in my face. look at his you tube aeducator

u/nerja07 • 1 points

I used it for 6 months with zero results

u/Background-Limit-358 • 1 points

were you applying it correctly ?

u/nerja07 • 1 points

Yes - I even contacted the owner for tips!!

u/Background-Limit-358 • 1 points

hmmmm

u/sakurababydoll • 2 points

thanks for sharing.this is super interesting. I wish they would be able to ship to Australia :(

u/Gingerpnw225 • 2 points

Welp, I had to order a small amount after reading this. I don’t have many areas that I’d want to add fat but I am almost 45 so wondering if I put a small amount on my cheeks, temples, if it could add some volume. Can you give us an idea of how much you add to your lotion or ratio of product?

u/SaintSiren • 4 points

The web site says the max recommended concentration is 2%

u/theejswann • 1 points

how did you do? the op said she added 1/4 of the vial to a big dove bottle of lotion.

u/m-rabia • 1 points

how did it work for you!?

u/TheKnown_Unknown • 1 points

how's the progress been in the end?

u/ohuwish • 2 points

So at the point your breast growth is at right now, do you still have to use the cream to maintain results or will they keep growing ?

u/anniesiaccc • 2 points

Nooo It’s like the fat cells are there, and won’t go away.. I haven’t used it in a month

u/ohuwish • 2 points

I just bought some! I’ll let you know how it goes

u/anncetta • 2 points

Updates??

u/theejswann • 1 points

How did it go???

u/ohuwish • 2 points

It didn’t work for me, used the whole vial and nothing

u/theejswann • 1 points

Dangit! Where did you apply it and for how long?

u/ohuwish • 1 points

On my butt I guess over a months time

u/Capable-Ice3402 • 2 points

did you use it in the same proportions as OP? It seems like she used 20-30% instead of recommended 2%?

u/ohuwish • 1 points

Yes

u/Capable-Ice3402 • 1 points

was it from lotioncrafter?

u/National_Ad9742 • 2 points

I wonder if this will work on plumping out my bone claw hands. I’ve been looking into things to help that. They are basically bones in a thin skin sleeve.

u/anniesiaccc • 3 points

Lmao I wondered that too out of curiosity It will build where hair follicles grow and precious subcutaneous fat has been stored My hands are still a double zero

u/stripeddogg • 1 points

Yeah, if you were applying with your fingers/hands wouldn't your fingers have gained some fat?

u/Big_Employment7919 • 2 points

this is amazing thanks for sharing

u/filthy_weeb_trash • 1 points

adifyline is pretty great. im trying to use it to put on more weight and while i dont know that its doing much on my legs damn if it isnt doing wonders for my face. i will say the leaner you are in an area the more noticeable it is though.

u/theejswann • 1 points

Wow! how many times have you used it so far? what areas of your face? I want to do cheeks. I wonder if I can use under eyes to plump there.

u/filthy_weeb_trash • 2 points

> Wow! how many times have you used it so far? what areas of your face?

2 weeks full face, 2 weeks upper to mid cheek, 2 weeks upper cheeks and spot treatment to deal with asymmetry. its not an overnight miracle, but the gradual effects are noticeable.

> I want to do cheeks. I wonder if I can use under eyes to plump there.

i have a friend who is applying it to his undereyes, from what ive seen of him it absolutely does something for them.

i hope you dont mind if i dont post my face here but heres a crop of my cheek area after a month and a week. progress is easy to miss if you dont take photos as a lot of it is subtle. evidently its doing something as i got asked for ID buying wine the other day, something i havent experienced in years.

https://files.catbox.moe/gaj2sq.png

https://files.catbox.moe/0nuhcy.png

yes im male.

u/theejswann • 1 points

Thank you! It's been 2 days and lotioncrafter hasn't even shipped my order yet. Which picture is which?

u/filthy_weeb_trash • 1 points

latter is the more recent one. my source isnt lotioncrafter but lotioncrafter is probably your best bet.

u/theejswann • 1 points

Mine should be here tomorrow!!@ Did you use dmso? Do you think you friend would send you a before and after pict of his eyes cropped to share with me?

u/filthy_weeb_trash • 1 points

DSMO is stupidly bad for you, i recommend mixing into an aqueous lotion of your choice and itll work just fine at 2-5% concentration. ill ask him.

u/theejswann • 1 points

Mine just arrived! I'm a little nervous lol. What did you friend say about the pic?

u/filthy_weeb_trash • 1 points

i asked him and he hasnt really said yes or no lol, but i did link the thread

u/theejswann • 1 points

lol well thanks!

u/theejswann • 1 points

Also, how many times a day did you apply?

u/filthy_weeb_trash • 2 points

i do twice daily application of 5% adifyline in aqueous cream. another friend of mine says shes had good results with hers, and shes done 2% adifyline in aqueous cream for 2 months.

u/Ecstatic_Low_827 • 1 points

Does it make where you apply it get bigger slowly...so you have some control as to when to stop applying it?... Or do you wake up one day sorry that you applied it because it grows huge almost overnight? (which would be terrifying) To help- this is what I've researched:They say apple cider vinegar applied will make fat cells smaller- I haven't tried it though. There is also this weight loss cream that supposedly works: https://www.flexussports.com/products/amilean-fat-loss-lotion-with-2-aminophylline

u/adirik92 • 1 points

I have been trying this by adding a couple of drops adifyline to a moisturizer and applying it twice a day to my breasts and face and I’m surprised to confirm it is indeed working. In 2.5 weeks, my breast measurement grew by 3 cms (I’m always leveling on a tattoo on my back so I’m sure the measurement is accurate) and they feel and look bouncier. My face is also noticeably more plump, to the point that I will stop and apply it only to my under eyes for another week or two. Extremely happy with the results and curious to see whether it lasts if I discontinue using this peptide.

u/Throwmeawaythanks99 • 1 points

Hi, have the results lasted?

u/carveryjoie • 1 points

Where did you buy your adifyline?

u/TheKnown_Unknown • 1 points

keen to hear how this has developed since then for you?

u/stripeddogg • 1 points

are the results permanent? since it's fat I'm guessing it stays until you lose it?

u/kleopatra_kardashian • 1 points

Did you only gain weight in your breasts or overall?